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Simultaneous 3D imaging of vascular and neuronal networks in mouse spinal cord tissue

Given that blood supply to the brain and spinal cord is fundamental to central nervous system (CNS) physiology and pathology, it's not surprising that trauma and disease in spinal cord blood vessels and neurons lead to a range of neurodegenerative pathologies and other serious consequences. However, current imaging tools do not generate sufficient dimensionality, resolution, contrast and other factors critical to investigating neurodegenerative pathologies and spinal-cord-injuries, as well as to understanding the relationship between vascular and neuronal systems.

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