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Low cholesterol slows HIV progression

Why some HIV-infected people experience much slower disease progression, even without medication? It has to do with cholesterol levels in specific immune cells, scientists have found.

"A fascinating aspect of the AIDS epidemic is that a small percentage of HIV-1-infected persons maintain a relatively normal number of CD4 T cells (Th cells) and low viral load for many years without receiving antiviral therapy," said Giovanna Rappocciolo from University of Pittsburgh.

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