Pocket-Lint: A video from Google's YouTube channel (update: the video is now private, but there's a mirror here) introduces a new Gmail interface. It's based on the Preview theme that's already available in Gmail, but there are many other changes: an action bar that uses icons instead of text labels, a completely new interface for conversations, profile pictures next to contacts, a flexible layout that adapts to any window size, display density options like in Google Docs, resizable chat/labels sections, new high-definition themes and an updated search box that includes advanced options.
But you can still go back to the old layout if you prefer.
Overall, this looks like a decent UI update for people that use multiple Google services.
Spam runs rampant on Gmail, but you have options.