Detecting the absorption of light from just a single molecule

One of the not-so-secret desires of the optical imaging community is "single molecule" imaging. This is usually not quite what it seems though. Most of us don't expect to get a picture of where all the atomic nuclei or electrons are. Instead, what we usually think of is being able to say the optical signal from a particular location is due to a single molecule. So, in that respect, it is probably more accurate to call this single molecule location mapping.

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